Differentiation of a blood vessel into an artery or a vein is regulated by which of the following?
a. notch signaling
b. wnt signaling
c. ephrins and ephs
d. shh signaling

Notch signaling

Explanation:

Notch signalling operates in many cell type at different stages during development. The notch signalling regulates cell fate, cell proliferation, cell differentiation and cell death. The notch cascade contains notch as well as notch ligands. It also contains intracellular protein which transmits the notch signal to the nucleus of the cell. It is important for the regulation of embryonic development.