Which of the following is a change in the sequence that leads to formation of a stop codon?
missense mutation
nonsense mutation
silent mutation
deletion mutation

-nonsense mutation

Explanation:

Non-sense mutations can be described as mutations that to formation of a non-sense or stop codon in mRNA made from mutated gene. There are a  total of 64 codons, out of which 61 code for specific amino acids and 3 codons act as stop codon or non-sense codons.

As these codons provide signal for termination of transcription, non-sense mutations lead to formation of a incomplete or truncated proteins due to premature termination of translation.

Thus, the correct answer is  'second option.'

it also supports my hypothesis. if you rest first you can squeeze the clothespin more times. from the data i collected the average of the eight people concluded exercise makes your muscles more fatigued and less able to squeeze the clothespin compared to resting before squeezing.