The disease bullous permphigoid results in the destruction of protein within the basement membrane that holds the epidermis and dermis together . how would this likely impact the epidermis . would the skin be an effective barrier?

stimulus is a change in the environment that causes an organism to react. the response is the reaction to the stimulus. some examples of stimuli for zebras are drought, to many predators, and bad feeding grounds such as dead grass or plants. zebras respond to stimuli just like all other living organisms