Histamine increases blood flow and vascular permeability. this would account for all of the following changes that occur during inflammation, exceptswelling of the inflamed tissue. redness of the inflamed tissue. movement of defense proteins and cells into the interstitial space. chemotaxis of phagocytes. heat of the inflamed tissue.

chemotaxis of phagocytes

Explanation:

Histamine is a chemical involved in inflammation but it also has role as a neurotransmmiter in central nervous system and uterus It is synthesized by the two types of cells:  basophils and mast cells and it acts via binding to its receptors (histamine receptors). Roles of histamine are:

the abdomen (less formally called the belly, stomach, tummy or midriff) constitutes the part of the body between the thorax (chest) and pelvis, in humans and in other vertebrates. the region occupied by the abdomen is termed the abdominal cavity. the stomach secretes acid and enzymes that digest food. ridges of muscle tissue called rugae line the stomach. the stomach muscles contract periodically, churning food to enhance digestion. the pyloric sphincter is a muscular valve that opens to allow food to pass from the stomach to the small intestine.