Plasmodium is a protist that causes malaria. a hypothetical drug targeting the outer membrane of plasmodium could cause cell rupture of the protist and prevent malaria. what specific protist structure would this drug target

Pellicle.  

Explanation:

Malaria is the most significant parasitic disease of human. The disease is caused by protozoan of the genus Plasmodium. The most serious malignant malaria is caused by Plasmodium falciparum. It is transmitted by the female Anopheles  mosquito. Plasmodium is a protist that cause malaria. Different types of species of the plasmodium are: P.vivax, P.malaria, P.ovale and P.falciparum which causes the most serious malignant called malaria.  

Protist have animal-cell like membrane and is plasmodium is the example of protist. Its contain single nuclei or many nuclei. On a paracium exterior found a pellicle. Pellicle is a layered structure which surrounds the cells in many types of protozoa and also surrounds the cytoplasm. It is the non-extracellular like the cell wall of plants.