Research shows that neurofibrillary tangles associated with the disintegration of microtubules are the primary cause of alzheimer's disease. if microtubules disintegrate, what then might happen to brain cells?

Without microtubule, the brain cell will die

Explanation:

Microtubules are very essential for determining the the shape of the cell. Physically, they help in the movement of substance with in cells. The major function of microtubule is to hold different parts of the brain cells in intact position and also provide shape to the long elongated brain cell. Without microtubule, the brain cell may become lose and it may also lose its shape. It keeps the distant part of the brain cells alive and without it the brain cell may become dead.

a tetrad is the foursome during meiosis made by two homologous chromosomes that have each already replicated into a pair of sister chromatids.