Inflammation, your skin, and macrophages are all part of the body's immune system response to a pathogen. allergic general practiced specific

Inflammation, your skin, and macrophages are all part of the body's general immune system response to a pathogen. 
General or non-specific immune response include the cells and mechanisms for defending the host from infection, but those mechanisms are not long-lasting. It includes anatomical barriers (like skin or mucose membranes),recruitment of immune cells to sites of infection, removal of pathogens by white blood cells (like macrophages)…

Calcinosis is the diagnostic term that means an abnormal buildup of calcium on the kneecap (patellar) surface. it is a term uses to describe a group of disorders in which calcium deposits form in the skin. it is also referred to the abnormal deposit of calcium phosphate.