Antigone’s death causes the audience to feel
animosity toward creon
anger toward haemon
distrust toward the gods
disrespect toward antigone

It was animosity towards Creon.  He could have saved her but was too late in doing so.  She had and this also led the suicide of Haemon and finally the death of Eurydice.  Creaon is left alone and goes on with the business of ruling as if the lives of those does not matter and this brings about a feeling of animosity.